Nguyen Minh Duc, PhD., Prof.

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Name

Nguyen Minh Duc

Position

Head of Department of Botany - Pharmacognosy

Speciality

Pharmacognosy

E-mail

nguyenminhduc@tdtu.edu.vn

Education

PhD; Hiroshima University, Japan (1994)

MSc of Pharmacy; University of Medicine and Pharmacy, Ho Chi Minh City (1982)

BSc of Pharmacy; University of Medicine and Pharmacy, Ho Chi Minh City (1979)

Career

2019 - now: Head of Department of Pharmacognosy - Botany

09/2015 – 2019: Dean of Faculty of Pharmacy, Ton Duc Thang University

1999 - 08/2015: Head of Science and Technology Management department, University of Medicine and Pharmacy, Ho Chi Minh City

1979 - Present: Lecturer, University of Medicine and Pharmacy, Ho Chi Minh City

Representative Publication
  1. Minh Nguyen, H., Truong Nguyen, H., Win, N., Piow Wong, C., Vu Huynh, K.L., Hoang, N.N., Do, K.M., Thi Nguyen, H., Viet Ho, D., Duc Nguyen, M. and Morita, H., 2020. Antimelanogenic Activity of Ocotillol‐Type Saponins from Panax vietnamensis. Chemistry & Biodiversity, 17(5), p.e2000037. Link.
  2. Ma, C.T., Cho, E., Nguyen, H.T., Wu, B., Van Le, T.H., Oh, K.B., Kwon, S.W., Nguyen, M.D. and Park, J.H., 2020. Malacinones A and B, two novel sesquiterpenoids with 6/6/5 tricyclic ring system from the agarwood of Aquilaria malaccensis. Tetrahedron Letters, 61(1), p.151355. Link.
  3. Lee, D., Lee, J., Vu-Huynh, K.L., Van Le, T.H., Tuoi Do, T.H., Hwang, G.S., Park, J.H., Kang, K.S., Nguyen, M.D. and Yamabe, N., 2019. Protective Effect of Panaxynol Isolated from Panax vietnamensis against Cisplatin-Induced Renal Damage: In Vitro and In Vivo Studies. Biomolecules, 9(12), p.890. Link.
  4. Vu-Huynh, K.L., Le, T.H.V., Nguyen, H.T., Kim, H.M., Kang, K.S., Park, J.H. and Nguyen, M.D., 2019. Increase in Protective Effect of Panax vietnamensis by Heat Processing on Cisplatin-Induced Kidney Cell Toxicity. Molecules, 24(24), p.4627. Link.
  5. Nguyen, L.T.T., Lai, N.T., Nguyen, L.T., Nguyen, H.T., Nguyen, D.M. and Nguyen, L.H.D., 2016. Thoreliolides A and B, two polyisoprenylated benzoylphloroglucinol derivatives with a new carbon skeleton from the fruits of Calophyllum thorelii. Tetrahedron Letters, 57(25), pp.2737-2741. Link.
  6. Nguyen, H.T., Lee, D.K., Lee, W.J., Lee, G., Yoon, S.J., Shin, B.K., Nguyen, M.D., Park, J.H., Lee, J. and Kwon, S.W., 2016. UPLC-QTOFMS based metabolomics followed by stepwise partial least square-discriminant analysis (PLS-DA) explore the possible relation between the variations in secondary metabolites and the phylogenetic divergences of the genus Panax. Journal of Chromatography B, 1012, pp.61-68. Link.
  7. Van Le, T.H., Lee, G.J., Vu, H.K.L., Kwon, S.W., Nguyen, N.K., Park, J.H. and Nguyen, M.D., 2015. Ginseng saponins in different parts of Panax vietnamensis. Chemical and Pharmaceutical Bulletin, 63(11), pp.950-954. Link. 
  8. Jeong, J.J., Van Le, T.H., Lee, S.Y., Eun, S.H., Nguyen, M.D., Park, J.H. and Kim, D.H., 2015. Anti-inflammatory effects of vina-ginsenoside R2 and majonoside R2 isolated from Panax vietnamensis and their metabolites in lipopolysaccharide-stimulated macrophages. International immunopharmacology, 28(1), pp.700-706. Link. 
  9. Lee, S.Y., Jeong, J.J., Le, T.H.V., Eun, S.H., Nguyen, M.D., Park, J.H. and Kim, D.H., 2015. Ocotillol, a majonoside R2 metabolite, ameliorates 2, 4, 6-trinitrobenzenesulfonic acid-induced colitis in mice by restoring the balance of Th17/Treg cells. Journal of agricultural and food chemistry, 63(31), pp.7024-7031. Link. 
  10. Van Le, T.H., Lee, S.Y., Lee, G.J., Nguyen, N.K., Park, J.H. and Nguyen, M.D., 2015. Effects of steaming on saponin compositions and antiproliferative activity of Vietnamese ginseng. Journal of ginseng research, 39(3), pp.274-278. Link.
  11. Van Le, T.H., Lee, S.Y., Kim, T.R., Kim, J.Y., Kwon, S.W., Nguyen, N.K., Park, J.H. and Nguyen, M.D., 2014. Processed Vietnamese ginseng: preliminary results in chemistry and biological activity. Journal of Ginseng Research, 38(2), pp.154-159. Link. 
  12. Nguyen, L.T.T., Nguyen, D.M. and Nguyen, L.H.D., 2013. A new xanthone from the bark of Calophyllum thorelii. Natural product research, 27(6), pp.563-567. Link.
  13. Nguyen, L.T.T., Nguyen, H.T., Barbič, M., Brunner, G., Heilmann, J., Pham, H.D., Nguyen, D.M. and Nguyen, L.H.D., 2012. Polyisoprenylated acylphloroglucinols and a polyisoprenylated tetracyclic xanthone from the bark of Calophyllum thorelii. Tetrahedron Letters, 53(34), pp.4487-4493. Link.
  14. Dinh, V., Zhang, H.P., Duc, N.M., Tuu, N.V. and Qin, G.W., 2006. A new geranyl flavanone from Macaranga triloba. Journal of Asian natural products research, 8(1-2), pp.155-158. Link. 
  15. Nguyen, T.D., Villard, P.H., Barlatier, A., Elsisi, A.E., Jouve, E., Duc, N.M., Sauze, C., Durand, A. and Lacarelle, B., 2000. Panax vietnamensis protects mice against carbon tetrachloride-induced hepatotoxicity without any modification of CYP2E1 gene expression. Planta medica, 66(08), pp.714-719. Link.
  16. Konoshima, T., Takasaki, M., Ichiishi, E., Murakami, T., Tokuda, H., Nishino, H., Duc, N.M., Kasai, R. and Yamasaki, K., 1999. Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis. Cancer letters, 147(1-2), pp.11-16. Link.
  17. Konoshima, T., Takasaki, M., Tokuda, H., NISHINO, H., DUC, N.M., KASAI, R. and YAMASAKI, K., 1998. Anti-tumor-promoting Activity of Majonoside-R2 from Vietnamese Ginseng, Panax vietnamensis HA et GRUSHV.(I). Biological and Pharmaceutical Bulletin, 21(8), pp.834-838. Link.
  18. Kaneko, T., Ohtani, K., Kasai, R., Yamasaki, K. and Nguyen, M.D., 1998. n-Alkyl glycosides and p-hydroxybenzoyloxy glucose from fruits of Crescentia cujete. Phytochemistry, 47(2), pp.259-263. Link. 
  19. Huong, N.T.T., Matsumoto, K., Nham, N.T., Quang, H., Duc, N.M., Yamasaki, K. and Watanabe, H., 1997. Effect of Vietnamese Ginseng on the phagocytosis in vitro and in vivo. Phytomedicine, 4(4), pp.341-346. Link.
  20. Kaneko, T., Ohtani, K., Kasai, R., Yamasaki, K. and Duc, N.M., 1997. Iridoids and iridoid glucosides from fruits of Crescentia cujete. Phytochemistry, 46(5), pp.907-910. Link. 
  21. Huong, N.T.T., Matsumoto, K., Yamasaki, K., Duc, N.M., Nham, N.T. and Watanabe, H., 1997. Majonoside-R2, a major constituent of Vietnamese ginseng, attenuates opioid-induced antinociception. Pharmacology Biochemistry and Behavior, 57(1-2), pp.285-291. Link.
  22. Huong, N.T.T., Matsumoto, K., Yamasaki, K., Duc, N.M., Nham, N.T. and Watanabe, H., 1996. Effects of vietnamese ginseng on opioid agonist—and conditioned fear stress-induced antinociception. Phytomedicine, 3(1), pp.33-39. Link. 
  23. Huong, N.T.T., Matsumoto, K., Yamasaki, K., Duc, N.M., Nham, N.T. and Watanabe, H., 1996. Effects of majonoside-R2 on pentobarbital sleep and gastric lesion in psychologically stressed mice. Pharmacology Biochemistry and Behavior, 53(4), pp.957-963. Link.
  24. Huong, N.T.T., Matsumoto, K., Yamasaki, K., Duc, N.M., Nham, N.T. and Watanabe, H., 1996. The possible involvement of GABAA systems in the antinarcotic effect of majonoside-R2, a major constituent of Vietnamese ginseng, in mice. The Japanese Journal of Pharmacology, 71(4), pp.345-349. Link. 
  25. Huong, N.T.T., Matsumoto, K., Yamasaki, K., Duc, N.M., Nham, N.T. and Watanabe, H., 1995. Crude sponin extracted from Vietnamese ginseng and its major constituent majonoside-R2 attenuate the psychological stress-and foot-shock stress-induced antinociception in mice. Pharmacology Biochemistry and Behavior, 52(2), pp.427-432. Link. 
  26. Nham, N.T., De, P.V., Luan, T.C., Duc, N.M., Shibata, S., Tanaka, O. and Kasai, R., 1995. Pharmacognostical and chemical studies on Vietnamese ginseng, Panax vietnamensis Ha et Grushv.(Araliaceae).  Jpn. Bot., 70, pp.1-10. Link.
  27. Maeda, C., Ohtani, K., Kasai, R., Yamasaki, K., Duc, N.M., Nham, N.T. and Cu, N.K.Q., 1994. Oleanane and ursane glycosides from Schefflera octophylla. Phytochemistry, 37(4), pp.1131-1137. Link. 
  28. Ito, A., Kasai, R., Yamasaki, K., Duc, N.M. and Nham, N.T., 1994. Lignan glycosides from bark of Albizzia myriophylla. Phytochemistry, 37(5), pp.1455-1458. Link. 
  29. Duc, N.M., Kasai, R., Ohtani, K., Ito, A., Nham, N.T., Yamasaki, K. and Tanaka, O., 1994. Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. collected in central Vietnam. III. Chemical & pharmaceutical bulletin, 42(3), pp.634-640. Link. 
  30. Duc, N.M., KASAI, R., OHTANI, K., ITO, A., NHAM, N.T., YAMASAKI, K. and TANAKA, O., 1994. Saponins from Vietnamese ginseng, Panax vietnamensis HA et Grushv. Collected in central Vietnam. II. Chemical and pharmaceutical bulletin, 42(1), pp.115-122. Link.
  31. ITO, A., KASAI, R., DUC, N.M., OHTANI, K., NHAM, N.T. and YAMASAKI, K., 1994. Alkaloid from bark of Albizzia myriophylla. Chemical and pharmaceutical bulletin, 42(9), pp.1966-1967. Link. 
  32. YAMASAKI, K. and TANAKA, O., 1994. Saponins from Vietnamese Ginseng, Panax vietnamensis HA et Grushv. Collected in central Vietnam. II. Chemical and Pharmaceutical Bulletin, 42(1), pp.115-122. Link. 
  33. Nguyen, M.D., Nguyen, T.N., Kasai, R., Ito, A., Yamasaki, K. and Tanaka, O., 1993. Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. I. Chemical & pharmaceutical bulletin, 41(11), pp.2010-2014. Link. 
  34. Nguyen, M.D., Nguyen, T.N., Kasai, R., Ito, A., Yamasaki, K. and Tanaka, O., 1993. Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. I. Chemical & pharmaceutical bulletin, 41(11), pp.2010-2014. Link.
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