
Tiến sĩ. Lê Quốc Việt
Chức danh: Phó Trưởng Khoa, Trưởng Bộ môn
Chuyên môn: Bào chế - Hóa Lý Dược
Email: lequocviet@tdtu.edu.vn
🔬 Hướng nghiên cứu chính
- Phát triển các vật liệu sinh học mới trong bào chế thuốc nano
- Phát triển hệ phân phối thuốc nano ứng dụng trong điều trị ung thư
- Đánh giá hoạt tính của hệ thuốc nano trên hệ miễn dịch
- Ứng dụng công nghệ thuốc nano trong phát triển vaccine thế hệ mới
🎓 Quá trình đào tạo
- 2021: Tiến sĩ, chuyên ngành Bào chế - Hóa Lý Dược, Đại học quốc gia Seoul, Hàn Quốc
- 2013: Dược sĩ đại học, Đại học Y Dược TP. Hồ Chí Minh
🏢 Quá trình công tác
- 11/2021- nay : Khoa Dược, Trường Đại học Tôn Đức Thắng
📑 Công bố khoa học
Patent
- Oh, Yu-Kyoung; Shin, Young Kee; Shim, Gayong; Yang, Hobin; Le, Quoc-Viet. Pharmaceutical composition for treating cancer, containing lipid-photothermal nanoparticle having antibody bound to surface, WIPO, 2021, Patent No. WO/2021/201451
Quốc tế
- Shim, Gayong, Seungbeom Ko, Dongyoon Kim, Quoc-Viet Le, Gyu Thae Park, Jaiwoo Lee, Taekhyun Kwon, Han-Gon Choi, Young Bong Kim, and Yu-Kyoung Oh. "Light-switchable systems for remotely controlled drug delivery." Journal of Controlled Release 267 (2017): 67-79.
- Shim, Gayong, Dongyoon Kim, Quoc-Viet Le, Gyu T. Park, Taekhyun Kwon, and Yu-Kyoung Oh. "Nonviral delivery systems for cancer gene therapy: strategies and challenges." Current gene therapy 18, no. 1 (2018): 3-20.
- Le, Quoc-Viet, Jinjoo Choi, and Yu-Kyoung Oh. "Nano delivery systems and cancer immunotherapy." Journal of Pharmaceutical Investigation 48, no. 5 (2018): 527-539.
- Le, Quoc-Viet, Geon Yang, Yina Wu, Ho Won Jang, Mohammadreza Shokouhimehr, and Yu-Kyoung Oh. "Nanomaterials for modulating innate immune cells in cancer immunotherapy." Asian Journal of Pharmaceutical Sciences 14, no. 1 (2019): 16-29.
- Le, Quoc-Viet, Juhan Suh, and Yu-Kyoung Oh. "Nanomaterial-based modulation of tumor microenvironments for enhancing chemo/immunotherapy." The AAPS Journal 21, no. 4 (2019): 1-19.
- Shim, Gayong, Quoc-Viet Le, Juhan Suh, Sunhee Choi, Gunwoo Kim, Han-Gon Choi, Young Bong Kim, Robert B. Macgregor Jr, and Yu-Kyoung Oh. "Sequential activation of anticancer therapy triggered by tumor microenvironment-selective imaging." Journal of Controlled Release 298 (2019): 110-119.
- Kim, Dongyoon, Quoc-Viet Le, Young Bong Kim, and Yu-Kyoung Oh. "Safety and photochemotherapeutic application of poly (γ-glutamic acid)-based biopolymeric nanoparticle." Acta Pharmaceutica Sinica B 9, no. 3 (2019): 565-574.
- Le, Quoc-Viet, Juhan Suh, Jin Joo Choi, Gyu Thae Park, Jung Weon Lee, Gayong Shim, and Yu-Kyoung Oh. "In situ nanoadjuvant-assembled tumor vaccine for preventing long-term recurrence." ACS nano 13, no. 7 (2019): 7442-7462.
- Lee, Jaiwoo1, Quoc-Viet Le1, Geon Yang, and Yu-Kyoung Oh. "Cas9-edited immune checkpoint blockade PD-1 DNA polyaptamer hydrogel for cancer immunotherapy." Biomaterials 218 (2019): 119359. (1 co-first authors).
- Choi, Jin Joo1, Quoc-Viet Le1, Dongho Kim, Young Bong Kim, Gayong Shim, and Yu-Kyoung Oh. "High molecular weight chitosan-complexed RNA nanoadjuvant for effective cancer immunotherapy." Pharmaceutics 11, no. 12 (2019): 680. (1 co-first authors).
- Yang, Hobin1, Quoc-Viet Le1, Gayong Shim, Yu-Kyoung Oh, and Young Kee Shin. "Molecular engineering of antibodies for site-specific conjugation to lipid polydopamine hybrid nanoparticles." Acta Pharmaceutica Sinica B 10, no. 11 (2020): 2212-2226. (1 co-first authors).
- Shim, Gayong, Seungbeom Ko, Joo Yeon Park, Ju Han Suh, Quoc-Viet Le, Dongyoon Kim, Young Bong Kim et al. "Tannic acid-functionalized boron nitride nanosheets for theranostics." Journal of Controlled Release 327 (2020): 616-626.
- Kim, Dongyoon1, Quoc-Viet Le1, Yina Wu, Jinwon Park, and Yu-Kyoung Oh. "Nanovesicle-mediated delivery systems for CRISPR/Cas genome editing." Pharmaceutics 12, no. 12 (2020): 1233. (1 co-first authors).
- Le, Quoc-Viet1, Jaiwoo Lee1, Hobin Lee, Gayong Shim, and Yu-Kyoung Oh. "Cell membrane-derived vesicles for delivery of therapeutic agents." Acta Pharmaceutica Sinica B 11, no. 8 (2021): 2096-2113. (1 co-first authors).
- Le, Quoc‐Viet, Dongyoon Kim, Jaiwoo Lee, Gayong Shim, and Yu‐Kyoung Oh. "Photosensitizer‐Free Phototherapy with Peptide Micelle Nanoadjuvants for Cancer Vaccine against Metastasis of Melanoma." Advanced Therapeutics 4, no. 8 (2021): 2000288.
- Park, Jinwon, Jaehyun Choi, Dae-Duk Kim, Seunghee Lee, Bongjin Lee, Yunhee Lee, Sanghee Kim, Sungwon Kwon, Minsoo Noh, Mi-Ock Lee, Quoc-Viet Le*, and Yu-Kyoung Oh*. "Bioactive lipids and their derivatives in biomedical applications." Biomolecules & Therapeutics 29, no. 5 (2021): 465.
- Lee, Jaiwoo, Dongyoon Kim, Quoc-Viet Le*, and Yu-Kyoung Oh*. "Nanotherapeutics for immune network modulation in tumor microenvironments." Seminars in cancer biology. Academic Press, 2021.
- Le, Quoc-Viet, Jaiwoo Lee, Junho Byun, Gayong Shim, and Yu-Kyoung Oh. "DNA-based artificial dendritic cells for in situ cytotoxic T cell stimulation and immunotherapy." Bioactive Materials (2021).
Book chapter
- Shim, Gayong, Dongyoon Kim, Quoc-Viet Le, Junho Byun, Jinwon Park, and Yu-Kyoung Oh. "Biomaterials for gene editing therapeutics." In Biomaterials for Cancer Therapeutics, pp. 187-231. Woodhead Publishing, 2020.
🎗️ Giải thưởng
- Outstanding paper award, Seoul National University 2020. “In Situ Nanoadjuvant-Assembled Tumor Vaccine for Preventing Long-Term Recurrence”.