TS. Nguyễn Minh Hiền

TS. Nguyễn Minh Hiền

Họ và tên

Nguyễn Minh Hiền

Chức vụ

Trợ lý Trưởng Khoa - Giảng viên

Chuyên môn

Khoa học dược - hợp chất tự nhiên

E-mail

nguyenminhhien@tdtu.edu.vn

Quá trình đào tạo

2019: Tiến sĩ chuyên ngành hóa dược, Đại học Toyama, Nhật Bản

2011: Thạc sĩ chuyên ngành hóa hữu cơ, Đại học Cần Thơ

2008: Đại học chuyên ngành hóa, Đại học Cần Thơ

Quá trình công tác chuyên môn

2019-nay: Khoa Dược, Đại học Tôn Đức Thắng

2011-2015: Kiểm nghiệm viên QC, Vemedim Cần Thơ
Giải thưởng

9/2022-2/2023: Học bổng học giả Fulbright Việt Nam, Mỹ

9/2015-3/2019: Học bổng nghiên cứu sinh chính phủ Nhật Bản

Công trình công bố chủ yếu

International papers

  1. Visarut B, Sornkanok V, Kittipong S,Asma B., Nguyen AB,  Thach UD,  Do BH, Van SD, Kiep MD, Nguyen HM (2023) Antioxidant, Anti-Skin aging, Anti-inflammatory, and Anti-acetylcholinesterase activities of Rourea oligophlebia extracts. Chem Biodivers.  DOI: 10.1002/cbdv.202201096.
  2. Linh TKN, Hung QV, Hanh NTH, Thi VAT, Nguyen HM, Ty VP, Hang PTN, Thanh Pham & Duc VH (2023) Structure revision and absolute configuration of 5,7-diepi-2α-hydroxyoplopanone and anti-osteoporotic activities of sesquiterpenoids from the rhizomes of Homalomena pendula. Nat Prod Res 20:1-10.
  3. Hien Bich Thi Le, Van Anh Thi Tran, Nguyen HM, Linh Thuy Khanh Nguyen, Duc Viet Ho and Hoai Thi Nguyen (2023) Aspidiata E, a new spirostanol saponin from Aspidistra triradiata and its Cytotoxic Activity, Nat Prod Comm 18: 1-7.
  4. Iksen I, Wasita W, Tanakrit W, Chutipa S, Natapol P, Natsaranyatron S, Nguyen HM & Varisa P (2023) Identifying molecular targets of Aspiletrein‑derived steroidal saponins in lung cancer using network pharmacology and molecular docking‑based assessments. Sci Rep 13:1545-1557.
  5. 5. Hien Bich Thi Le, Duc Viet Ho,  Nguyen HM, Van Anh Thi Tran, Hoai Thi Nguyen (2023) Aspidiatas C and D, two new spirostanol saponins from Aspidistra triradiata and their cytotoxic activities. Nat Prod Res 26;1-9, doi: 10.1080/14786419.2023.2204432.
  6. Kiep MD, Takeshi K, Nguyen HM, Naoki I, Chigusa S, Ken-Ichi S, Morita H (2022) Seco- and isopimarane diterpenoids from Kaempferia marginata rhizomes and their NO inhibition activities. Phytochem, 25, 113510.
  7. Wasita W., Nguyen HM, Ho DV, Nguyen HT, Pithi C, Chanida V, Varisa P (2022) Aspiletrein A induces apoptosis cell death via increasing reactive oxygen species generation and AMPK activation in non-small-cell lung cancer cells. Int J Mol Sci, 23: 9258.
  8. Visarut B, Khwanlada K, Sornkanok V, Asma B, Kittipong S, Thien-Y. V, Kim LV H, Bao L, Huy TN, Kiep MD, Van SD, Nguyen HM (2022) Some antioxidant properties of components from the flower of Ochna integerrima and their beneficial effects on HaCaT keratinocytes and in silico analysis on tyrosinase. Chem Biodivers.  19: e202100882.
  9. Le HBT, Ho DV, Nguyen HM, Le AT, Tran TVA & Nguyen HT (2022) A new spirostanol steroid and a new spirostanol steroidal saponin from Aspidistra triradiata and their cytotoxic activities, Nat Prod Res, 1-10. DOI: 10.1080/14786419.2022.2095635.
  10. Le NT, Hoang NT, Van VTT,  Nguyen TPD,  Chau NHT,  Le NTN, Le HBT, HT Phung,  Nguyen HT, and   Nguyen HM (2022) Extraction of curcumin from turmeric residue (Curcuma longa L.) using deep eutectic solvents and surfactant solvents. Anal. Methods, 14, 850.
  11. Kodama T, Min-Kyoung Shin, Ton NLH, Nguyen HM, Dang SV, Shiokawa K, Hayakawa Y, Morita H (2022) Marginols A‒H, unprecedented pimarane diterpenoids from Kaempferia, Phytochemistry 169: 113109.
  12. Do MH, Khuat KVT, Huynh PT,   Nguyen LNT, Do BH, Pham PD,   Nguyen DH,  Nguyen HM, Thach UD (2022) Synthesis, characterization, and antibacterial activity of amino-functionalized microcrystalline cellulose derivatives from cotton fibers, Biomass Convers Biorefin. DOI 10.1007/s13399-022-02391-7.
  13. Do KM,  Shin MK, Kodama T,  Win NN, Prema P,  Nguyen HM, Hayakawa Y, Morita H (2021)  Flavanols and flavanes from Crinum asiaticum and their effects on LPS signaling pathway through the inhibition of NF-κB activation, Planta Med. DOI: 10.1055/a-1585-5877.
  1. Huy TN, Kim L VH, Nguyen HM, Huong TL, Thi HVL, Jeong HP, and Minh DN (2021) Evaluation of the saponin content in Panax vietnamensis acclimatized to Lam Dong province by HPLC–UV/CAD, Molecules 26: 5373-5385.
  2. Duc VH, Hoai TN, Y TV, Ty VP, and Nguyen HM (2021) Antioxidant activity of a new xanthone derivative from Aspidistra Letreae: In vitro and in silico studies, Chem Biodivers 14: e2001008.
  3. Nguyen HM, Hoai TN, Suthasinee S, Hang DB, Huy TN, Duc VH and Varisa P (2021), Antitumor activities of Aspiletrein A, a steroidal saponin from Aspidistra letreae, on non-small cell lung cancer cells, BMC Complementary Medicine and Therapies 21: 87-97.
  4. Ty VP, Hanh NTH, Hoai TN, Nguyen HM, Cong TH, Y TV, Anh TD, Nguyen HN, and Hang DB (2021) Anti-Inflammatory and antimicrobial activities of compounds isolated from Distichochlamys benenica, BioMed Research International, 6624347.
  5. Nguyen HM, Nguyen HT, Win NN, Wong CP, Vu HKL, Hoang NN, Do KM, Nguyen HT, Ho DV, Nguyen DM, Morita H (2020) Anti-melanogenic activity of ocotillol‐type saponins from Panax vietnamensis. Chem Biodivers 1: e2000037.
  6. Duc VH, Hanh NTH, Hung QV, Khan VN, Ty VP, Anh TL, Kiem VP, Nguyen HM, Hoai NT, Morita H (2020) Three new steroidal saponins from Aspidistra letreae plants and their cytotoxic activities. J Nat Med 74: 591-598.
  7. Khan VN, Duc VH, Nguyen HM, Thao TD, Kiem VP, Morita H, Jyrki H, Ain R and Hoai NT (2020) Chiro-Inositol derivatives from Chisocheton paniculatus showing Inhibition of nitric oxide production. J. Nat. Prod 83: 1201-1206.
  8. Ki DW, Kodama T, Ahmed H. El‐D, Wong CP, Nguyen HM, Do KM, Thai QM, Ton Nu LH, Morita H (2020) Chemical constituents of the Vietnamese marine sponge Gelliodes sp. and their cytotoxic activities. Chem Biodivers.  17: e2000303.
  9. Nguyen HM, Ito T, Win NN, Hung VQ, Hoai NT, Morita H (2019) A new sterol from the Vietnamese marine sponge Xestospongia testudinaria and its biological activities. Nat Prod Res 33: 1175-1181.
  10. Ki DW, Awouafack MD, Wong CP, Nguyen HM, Thai QM, Ton Nu LH, Morita H (2019) Brominated diphenyl ethers including a new tribromoiododiphenyl ether from the Vietnamese marine sponge Arenosclera sp. and their antibacterial activities. Chem Biodivers 16: e1800593.
  11. Hue BTB, Nguyen HM, Hieu MV, Thanh DLD, Son NH, De TQ, Morita H (2019) Facile sodium metabisulfite mediated systhesis of 1,2-disubstituted benzimidasoles and cytotoxicity evaluation. Heterocycles 98: 650-665.
  12. Ito T, Nguyen HM, Win NN, Hung VQ, Hoai NT, Morita H (2018) Three new sesquiterpene aminoquinones from a Vietnamese marine sponge of Spongia sp. and their biological activities. J Nat Med 72: 298-303.
  13. Nguyen HM, Ito T, Kurimoto S, Ogawa M, Win NN, Kodama T, Hung VQ, Hoai NT, Kubota T, Kobayashi J, Morita H (2017) New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities. Bioorg Med Chem Lett 27: 3043-3047.
  14. Duc HV, Hanh HTN, Hung VQ, Nguyen HM, Raal A, Hoai NT (2017) A new triterpene ester and other chemical constituents from the aerial parts of Anodendron paniculatum and their cytotoxic activity. J Asian Nat Prod Res 20: 188-194.
  15. Hoai NT, Duc HV, Hung VQ, Anh LT, Nguyen HM, Ito T, Kodama T, Morita H, Raal A (2017) Antibacterial activities of chemical constituents from the aerial parts of Hedyotis pilulifera. Pharm Biol 55: 787-791.
  16. Duc HV, Hanh HTN, Hung VQ, Kiem PV, Anh TL, Ty PV, Nguyen HM, Ito T, Kodama T, Morita H, Raal A, Hoai NT (2017) Cycloartane-type triterpene glycosides anopanins A-C with monoacyldigalactosylglycerols from Anodendron paniculatum. Phytochemistry 144: 113-118.
  17. Nguyen HM, Ito T, Win NN, Kodama T, Hung VQ, Hoai NT, Morita H (2016) New antibacterial sesquiterpene aminoquinones from a Vietnamese marine sponge of Spongia sp. Phytochem Lett 17: 288-292.

National papers

  1. Nguyen THN, Phan TL, Le PTA, Nguyen PK, Nguyen HA, Ton NLH, Nguyen BA, Le TKC, Nguyen HM (2023) Antioxidant and anti-inflammatory potential from Ochna integerrima Journal of Medicinal Materials, 28: 185-191.
  2. Nguyen Minh Hien (2022) Microscopic characteristics, antioxidant activities, and chemical compositions of Ochna integerrima leaves and stems. Journal of Medicinal Materials, 27: 227-234.
  3. Ton NLH, Vu HKL, Thach UD, Tran TTT, Le TNT, Do DT, Le TKC, Nguyen HM (2022) Microscopic characteristics, antioxidant activities, and chemical compositions of Ochna integerrima leaves and stems. Journal of Medicinal Materials, 27: 227-234.
  4. Ton NLH, Nguyen TV, Le TP and Nguyen HM (2021) Investigation on the antifungal coating of oranges. Can Tho University Journal of Science 57: 143-150 (Vietnamese).
  5. Ton NLH, Nguyen HM, Tran DL (2012) Study on the chemical components from (Achyranthes aspera). Can Tho University Journal of Science 21a: 114-118 (Vietnamese).
  6. Ton NLH, Nguyen HM, Tran DL (2011) Study on the chemical components from (Achyranthes aspera). Can Tho University Journal of Science 19b: 56-61 (Vietnamese).

International conferences

  1. The 63th Annual meeting of the Japanese society of Pharmaceutical Sciences, 2016, Toyama, Japan.
  2. The 64th Annual meeting of the Japanese society of Pharmaceutical Sciences, 2017, Chiba, Japan.
  3. The Second International Symposium on Toyama-Asia-Africa pharmaceutical network, 2017, Shang Dong, China.
  4. International symposium on scientific research of traditional medicine, 2017, Toyama, Japan.
  5. The fifth Toyama-Basel joint symposium on pharmaceutical research and drug development, 2018, Toyama, Japan.
  6. The 65th Annual meeting of the Japanese society of Pharmaceutical Sciences, 2018, Hiroshima, Japan.
  7. The 4th International conference on natural product discovery and development in the genomic era-the society for industrial microbiology and biotechnology (SIMB), 2023, San Diego, U.S.
  8. AsiaPharm V international conference (2023), Ton Duc Thang University, Vietnam.

Peer reviews

Chemistry and biodiversity (5); Chemistry Select (2); RCS advances (1)