Nhóm nghiên cứu Dược học và Khoa học Y sinh

Các công trình công bố của nhóm nghiên cứu

  • Iksen, Iksen, Natsaranyatron Singharajkomron, Ausana Wongtayan, Onsurang Wattanathamsan, Amaya Choonhapan, Sureeporn Wademonkolgorn, Hien Minh Nguyen, Trang Huyen Xuan Hoang, Hoai Thi Nguyen, and Varisa Pongrakhananon. "Unveiling the antimetastatic activity and molecular mechanism of montanine in lung cancer cells via the integration of network pharmacology approaches with in vitro and in vivo investigations." Journal of Integrative Medicine (2026).
  • Dieu, Trinh Quynh, Nguyen Tri Thuc, Mui Kieu Tieu Tho, Do Van Thanh Nhan, Chi Tran Linh, Mai Huynh Nhu, Nguyen Phuong Tram and Pham Duc Toan. “TRA-017, A Derivative of Tranilast, Protects against Hepatic Inflammation Induced by Lipopolysaccharide Administration.” Indian Journal of Animal Research (2026): n. pag.
  • Pham, Ty Viet, Thao Xuan Hoang, Nguyen Hoai Nguyen, Gia‐Buu Tran, and Bich Hang Do. "Phytochemical Profiling, Anti‐Inflammatory Effect, and Cytotoxicity to Cancer Cells of Essential Oil From Merremia hederacea Leaves." ChemistrySelect 11, no. 1 (2026): e03908.
  • Doan, Nghia Ai Thi, Hanh Nhu Thi Hoang, Tri‐Thuc Nguyen, Hoai Thi Nguyen, Thi Hong Van Le, Phuong Vu Luu, Cuong‐Quoc Nguyen, Hien Minh Nguyen, and Duc Viet Ho. "Antioxidant Activity and Tyrosinase Inhibition of Extracts and Flavonoids Isolated from the Leaves of Gymnosporia chevalieri: In Vitro and In Silico Studies." ChemistrySelect 10, no. 36 (2025): e00167.
  • Phan, Nguyen-Hong-Nhi, Thuc-Huy Duong, Thi-Kim-Dung Le, Huy Truong Nguyen, Ngoc-Hong Nguyen, and Jirapast Sichaem. "A New Benzoylphloroglucinol Isolated from the Fruits of Garcinia schomburgkiana." Chemistry of Natural Compounds (2025): 1-4.
  • Nguyen-Thi, Phuong-Trang, Nhat Thang Thi Nguyen, Huong Thuy Le, Thuy Trang Nguyen, and Giau Van Vo. "Advanced in Co-Delivery, Controllable Therapy using Microneedle: From Design to Therapeutic Effects." Pharmaceutical Research 43, no. 1 (2026): 95-121.
  • Thach, Ut Dong, Kim Ngan Luu, and Khanh Linh Chung. "Surface Modification of Nanocrystalline Cellulose for Optimized α‐Mangostin Loading and Therapeutic Applications." ChemistrySelect 10, no. 36 (2025): e01372.
  • Le, Nhan Trong, Thu Dong Duong, Duc Viet Ho, Hoai Thi Nguyen, and Hien Minh Nguyen. "Optimization of Ultrasound‐Assisted Extraction and Purification of Glycoalkaloids From Solanum Procumbens via Response Surface Methodology." ChemistrySelect 10, no. 42 (2025): e03767.
  • 9. Hoang, Hanh Nhu Thi, Linh Thuy Thi Tran, Nghia Ai Thi Doan, Hung Quoc Vo, Duyen Ngoc Thi Nguyen, Hoai Thi Nguyen, Anh Tuan Le, Hien Minh Nguyen, and Duc Viet Ho. "Two new dammarane-type triterpenoids and other constituents from Gymnosporia diversifolia with anti-inflammatory and cytotoxic activities." RSC advances 15, no. 51 (2025): 43284-43292.
  • Pham, Ty Viet, Anh Tuan Le, Bich Hang Do, and Gia-Buu Tran. "Essential oil of Munronia pinnata aerial parts: GC-MS composition, anti-cancer and anti-inflammatory effects, and molecular docking analysis." Journal of Biologically Active Products from Nature 15, no. 5 (2025): 539-555.
  • Pham, Ty Viet, Anh Tuan Le, Khanh‐Quynh Thi Nguyen, Bich Hang Do, and Gia‐Buu Tran. "Investigation of Chemical Constituents, Anti‐oxidant, Anti‐inflammatory, and Anti‐cancer Effects of the Essential Oil Isolated From Nosema cochinchinensis Leaves." Chemistry & Biodiversity 22, no. 12 (2025): e01760.
  • Nguyen, Huy Truong, Phuong-Mai To, Tri-Nhan Pham, Dinh-Minh-Tu Nguyen, Ngoc-Hong Nguyen, Jirapast Sichaem, and Nutthapol Funnimid. "Nitric oxide inhibitory compounds from Thai medicinal plants Averrhoa bilimbi and Schinus terebinthifolia." Records of Natural Products 20, no. 1 (2025): e25073593.
  • Le, Bao, Thi Nhat Hong Nguyen, and Seung-Hwan Yang. "Lactic acid bacteria alleviate neuronal excitotoxicity and extend Caenorhabditis elegans lifespan." Turkish Journal of Biology 49, no. 4 (2025): 392-399.
  • Thach, Ut Dong, and Thi Hoang Yen Le. "Facile Synthesis of Nano Polydopamine Cellulose Hydrogel Beads for Sustained Release of Ciprofloxacin." ChemistrySelect 10, no. 33 (2025): e01388.
  • Buranasudja, Visarut, Sornkanok Vimolmangkang, Kittipong Sanookpan, Hnin Mon Aung, Khanh Phuc Nguyen, An Thuy Pham Le, Nguyen Huong Thi Nguyen, Anh Tuan Le, Kiep Minh Do, and Hien Minh Nguyen. "Investigating the pharmacological properties of Eurya nitida Korth. Fruit extracts: promising anti-skin aging and anti-inflammatory effects." Natural Product Research (2025): 1-13.
  • Kim, Hayeong, Kibeom Jin, Ji Yeon Lee, Tae-hui Yang, Sejin Oh, Soochul Park, Gia-Buu Tran. "Functional properties of hard kombucha brewed with deep ocean water using Lachancea thermotolerans." Scientific Reports 15, no. 1 (2025): 26959.
  • Le, Huong Thuy, Tuan‐Dat Nguyen, Anh‐Ky Do, Thi‐Phuong Nguyen, Thi‐My‐Duyen Ngo, Thi‐Hoai‐Thu Nguyen, Xuan‐Hao Bui, Jirapast Sichaem, Thuc‐Huy Duong, and Ngoc‐Hong Nguyen. "Alpha‐Glucosidase and Nitric Oxide Inhibitors From Paramignya trimera Leaves and Dicranopteris linearis Spores: In Silico and In Vitro Aspects." Chemistry & Biodiversity 22, no. 9 (2025): e202500588.
  • Le, Bao, Dong Gyun Kim, Hyun Song, Phan Duy Khanh Giang, Ho Tue Han, and Seung Hwan Yang. "Lactobacillus helveticus CNU395 and L. paracasei CNU396 Alleviate Cognition in Scopolamine-Induced Cognitive Impairment Mice." Microorganisms 13, no. 8 (2025): 1714.
  • Kim, Sung Wook, Min-Jung Kang, Youngsun Kim, Woo Yeon Hwang, Aram Lee, Quoc-Viet Le, Ihn Han et al. "Novel biomarker discovery-coupled plasma therapy with enhanced tumor penetration for non-surgical treatment of cervical cancer." Journal of Controlled Release 384 (2025): 113946.
  • Ngo, Thi-My-Duyen, Thi Kim Ngan Tran, Thi Minh Thu Le, Mong Kha Tran, Huu Son Nguyen, Huy Truong Nguyen, and Kim Long Vu-Huynh. "Simultaneous Quantification of Main Saponins in Panax vietnamensis by HPLC-PDA/ELSD Using the Quantitative Analysis of Multi-Components by Single-Marker Method." Metabolites 15, no. 7 (2025): 419.
  • Pham, Ty Viet, Thien-Y. Vu, and Hien Minh Nguyen. "Chemical Profiles and Biological Activities of Essential Oil from Serissa japonica." Molecules 30, no. 12 (2025): 2485.
  • Nguyen, Phuong Tram, Quoc-Dung Tran Huynh, and Minh Duc Nguyen. "Isolation and purification of sinensetin, and in silico screening of phytochemicals from Orthosiphon aristatus (Blume) Miq. for anti-breast cancer activity." Natural Product Research (2025): 1-10.

Các công trình công bố nổi bật khác (thành viên nhóm là tác giả chính/tác giả gửi bài)

  • Nguyen HM, Nguyen PK, Le PTA, Nguyen THN, Vu HKL, LeTKC, Anjana Delpe A, Kenneth H.& Daniel R. (2024), Antioxidant, anti-tyrosinase, hepatoprotective, and anti-inflammatory potential in flowers and seeds of Ochna integerrima (Lour.) Merr, Natural Product Research 17:1-11.

  • Nguyen HM, Ty VP, Hung QV, Hoai TN, Linh TKN, Bao CN, Khanh L.C. and Duc V.H. (2024) Essential oil from Vietnamese Peperomia leptostachya Hook. & Arn. (Piperaceae): Chemical composition, antioxidant, anti-inflammatory, cytotoxic activities, and in silico analysis, Molecules 29: 2808-2822.

  • Thuy Le H, Vu YT, Duong GH, Le TK, Dang MK, Pham DD, Pham NK, Sichaem J, Nguyen NH, Duong TH. Bio-Guided Isolation of Alpha-Glucosidase Inhibitory Compounds from Vietnamese Lichen Roccella Montagnei. Chem Biodivers. 2024 Jul;21(7):e202400438. doi: 10.1002/cbdv.202400438. Epub 2024 May 28. PMID: 38581153. https://doi.org/10.1002/cbdv.202400438
  • Tran, G. B., Pham, T. V., Tuan Le, A., Nguyen, N. H., Vo, N. H. H., & Do, B. H. (2024). Chemical composition and the anti-inflammatory effect of volatile compounds from Anaxagorea luzonensis A. Gray. Zeitschrift fur Naturforschung. C, Journal of biosciences, 79(9-10), 329–336. https://doi.org/10.1515/znc-2023-0177
  • Le Q.V., Kang S., Lee J., Park H., Sun J.G., Lee J., Shim G. Size-Dependent Effect of Indocyanine Green Nanoimaging Agent for Metastatic Lymph Node Detection. Biomaterials Research 2024; 28, 0022.
  • Le, B., Hong, V. T. K., & Yang, S. H. (2024). Anti-Inflammatory Effects of Hydroethanolic Extract from Ehretia asperula on Lipopolysaccharide-Stimulated RAW264. 7 Macrophages. Journal of Microbiology and Biotechnology, 34(6), 1340. https://doi.org/10.4014/jmb.2403.03006
  • Nguyen, H. T., Phan, L. K., Huynh, K. L. V., Duong, T. H., Le, H. T., Hai-Yen, N. T., ... & Nguyen, M. D. (2023). Untargeted Metabolomics Approach for the Differentiation between Panax vietnamensis var. vietnamensis and Panax vietnamensis var. fuscidiscus. Metabolites, 13(6), 763.
  • Thuy Le H, Vu TY, Nguyen TV, Dinh Tri M, Pham NK, Truong Nguyen H, Nguyen NH, Nguyen HH, Duong TH. A New Carvotacetone Derivative from the Aerial Part of Sphaeranthus africanus. Chem Biodivers. 2023 Jun;20(6):e202300319. doi: 10.1002/cbdv.202300319. Epub 2023 May 30. PMID: 37183173. https://doi.org/10.1002/cbdv.202300319
  • Nguyen, H. T., Phan, L. K., Huynh, K. L. V., Duong, T. H., Le, H. T., Hai-Yen, N. T., ... & Nguyen, M. D. (2023). Untargeted Metabolomics Approach for the Differentiation between Panax vietnamensis var. vietnamensis and Panax vietnamensis var. fuscidiscus. Metabolites, 13(6), 763.
  • Tran, G. B., Ding, J., Ye, B., Liu, M., Yu, Y., Zha, Y., Dong, Z., Liu, K., Sudarshan, S., & Ding, H. F. (2023). Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma. Cancer research, 83(13), 2248–2261. https://doi.org/10.1158/0008-5472.CAN-22-3450
  • Le, B., Do, D. T., Nguyen, H. M., Do, B. H., & Le, H. T. (2022). Preparation, characterization, and anti-adhesive activity of Sulfate polysaccharide from Caulerpa lentillifera against Helicobacter pylori. Polymers, 14(22), 4993. https://doi.org/10.3390/polym14224993
  • Le, B., Kim, D. G., Phuoc, N. N., Linh, N. T. H., & Yang, S. H. (2022). Dietary supplementation with Pediococcus pentosaceus enhances the innate immune response in and promotes growth of Litopenaeus vannamei shrimp. Journal of Fish Diseases, 45(9), 1343-1354. https://doi.org/10.1111/jfd.13666
  •  Le Q.V., Lee J, Ko S, Kim H, Vu TY, Choe YS, Oh YK, Shim G. Enzyme-responsive macrocyclic metal complexes for biomedical imaging. Bioeng Transl Med. 2022 Dec 21;8(5):e10478
  • Nguyen, H. T., Vuong Bui, N. T., Kanhounnon, W. G., Vu Huynh, K. L., Nguyen, T.-V.-A., Nguyen, H. M., Do, M. H., Badawi, M., & Thach, U. D. (2021). Co-precipitation polymerization of dual functional monomers and polystyrene-co-divinylbenzene for ciprofloxacin imprinted polymer preparation [10.1039/D1RA05505D]. RSC Advances, 11(54), 34281-34290. https://doi.org/10.1039/D1RA05505D 
  • Thach, U. D., Nguyen Thi, H. H., Pham, T. D., Mai, H. D., & Nhu-Trang, T.-T. (2021). Synergetic Effect of Dual Functional Monomers in Molecularly Imprinted Polymer Preparation for Selective Solid Phase Extraction of Ciprofloxacin. Polymers, 13(16), 2788. https://www.mdpi.com/2073-4360/13/16/2788 
  • Le HT, Lee HJ, Cho J, Min HY, Lee JS, Lee SJ, Lee HY. Insulin-Like Growth Factor Binding Protein-3 Exerts Its Anti-Metastatic Effect in Aerodigestive Tract Cancers by Disrupting the Protein Stability of Vimentin. Cancers (Basel). 2021 Mar 2;13(5):1041. doi: 10.3390/cancers13051041. PMID: 33801272; PMCID: PMC7958122. https://doi.org/10.3390/cancers13051041
  • Le, B., Anh, P. T. N., & Yang, S. H. (2021). Polysaccharide derived from Nelumbo nucifera lotus plumule shows potential prebiotic activity and ameliorates insulin resistance in HepG2 cells. Polymers, 13(11), 1780. https://doi.org/10.3390/polym13111780
  • Nguyen, H. T., Vu-Huynh, K. L., Nguyen, H. M., Le, H. T., Le, T. H. V., Park, J. H., & Nguyen, M. D. (2021). Evaluation of the saponin content in Panax Vietnamensis acclimatized to lam dong province by HPLC–UV/CAD. Molecules, 26(17), 5373.
  • Le, Q.V.1; Lee, J.1; Lee, H.; Shim, G.; Oh, Y.K. Cell membrane-derived vesicles for delivery of therapeutic agents. Acta Pharm. Sin. B 2021, 11, 2096-2113. (1 co-first authors).
  • Le, Q.V., Kim, D., Lee, J., Shim, G.; Oh, Y.-K. Photosensitizer-Free Phototherapy with Peptide Micelle Nanoadjuvants for Cancer Vaccine against Metastasis of Melanoma. Adv. Therap. 2021, 4, 2000288.
  • Vu-Huynh, K. L., Nguyen, H. T., Van Le, T. H., Ma, C. T., Lee, G. J., Kwon, S. W., ... & Nguyen, M. D. (2020). Accumulation of saponins in underground parts of Panax vietnamensis at different ages analyzed by HPLC-UV/ELSD. Molecules, 25(13), 3086.
  • Vu-Huynh, K. L., Truong, B. V., Bui, V. H., Thanh, H. N. T., & Dang, V. S. (2020, November). Vaccinium chlaenophyllum (Ericaceae), a new species from the Central Highlands of Vietnam. In Annales Botanici Fennici (Vol. 58, No. 1-3, pp. 15-18). Finnish Zoological and Botanical Publishing Board.
  • Le, B., Ngoc, A. P. T., & Yang, S. H. (2020). Synbiotic fermented soymilk with Weissella cibaria FB069 and xylooligosaccharides prevents proliferation in human colon cancer cells. Journal of applied microbiology, 128(5), 1486-1496. https://doi.org/10.3390/foods9020181
  • Le, B., Anh, P. T. N., & Yang, S. H. (2020). Enhancement of the anti-inflammatory effect of mustard kimchi on RAW 264.7 macrophages by the Lactobacillus plantarum fermentation-mediated generation of phenolic compound derivatives. Foods, 9(2), 181.